Tag Archives: PGC-1alpha

An epigenetic mechanism for peripheral insulin resistance

PGC-1alpha is my favorite gene/protein to study, as it is essential for mitochondrial regulation, influential on many diseases and ageing.  I also am fascinated by the relatively new field of epigenetics and its relation to nutrition and health.  So you can understand my geeky giddiness when I found that a study by Barrès et al. (1) shows a link between them.  (Warning this is technically dense, I provide a summary at the end with my perspective) Because the skeletal muscle is the primary Read more [...]