An epigenetic mechanism for peripheral insulin resistance
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PGC-1alpha is my favorite gene/protein to study, as it is essential for mitochondrial regulation, influential on many diseases and ageing. I also am fascinated by the relatively new field of epigenetics and its relation to nutrition and health. So you can understand my geeky giddiness when I found that a study by Barrès et al. (1) shows a link between them. (Warning this is technically dense, I provide a summary at the end with my perspective)
Because the skeletal muscle is the primary Read more [...]