Weekend Update Leave a reply Some interesting links last week: Atherosclerotic plaques formed during a late and limited time period in life | e! Science News A short commentary in JAMA by David Ludwig on ultra-processing: Technology, Diet, and the Burden of Chronic Disease, April 6, 2011, Ludwig 305 (13): 1352 — JAMA Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease : Nature : Nature Publishing Group Ghrelin haplotypes associated with sweet consumption PLoS ONE: The Ghrelin Signalling System Is Involved in the Consumption of Sweets High fat diet in mice alters acetylation of Npas2, a circadian gene Epigenomics: maternal high-fat diet exposure in utero disrupts peripheral circadian gene expression in nonhuman primates [FASEB J. 2011] – PubMed result A nice cautious LATimes article on the strawberry/cancer research that was widely covered this week (which isn’t yet published) Strawberries cancer treatment: Ohio State University study tests strawberries – latimes.com Vitamin E activates PPARgamma, which increases adiponectin, giving a molecular pathway for its effects on insulin sensitivity. Vitamin E and adiponectin: proposed mechanism for vitamin E-induced improvement in insulin sensitivity [Nutr Rev. 2011] – PubMed result Holloszy and colleagues find that calorie restriction doesn’t increase mitochondrial biogenesis, unlike other research. Does calorie restriction induce mitochondrial biogenesis? A reevaluation. [FASEB J. 2011] – PubMed result Genome-wide survey of epigenetic marks Genetic Variations Affect Control of the Genome A nice summary by Dr. Goldfarb on the issue of antioxidant supplementation for exercise Active Voice: Understanding the Use of Antioxidant Supplementation with Exercise I have read some of this research and am convinced there are likely no benefits and possibly some risks to reducing adaptations to exercise if you take vitamin-antioxidants prior to exercise. An 80 year ‘Longevity Project’ that I had no idea was going on: The Longevity Project: Decades of Data Reveal Paths to Long Life – Veronique Greenwood – Life – The Atlantic Another study suggesting cramps don’t have anything to do with hydration or electrolyte balance: Risk factors associated with exercise associated muscle cramping (EAMC) – a prospective cohort study in ironman triathletes [Br J Sports Med. 2011] – PubMed result Megan summarizes research that examines links between our ‘natural environment’ and health: Verdant Nation: Is green good for our health? The last podcast at Obesity Panacea of Dr. Tremblay’s lecture: Preventing Obesity: “Preventive” Pharmacology (Podcast # 22) | Obesity Panacea A nice paper summarizing various areas of research in obesity: Obesity – Issues and Misconceptions About Obesity Cavities are contagious: Before a first date, ask for dental records Posted from Diigo. The rest of my favorite links are here.